Relapsing corticosteroid-dependent polyneuritis.

Relapsing Polyneuritis

Serum Antibodies Against a Reactive Site of Equine Myelin Protein 2 Linked to Polyneuritis Equi Found in Horses Diagnosed with EPM

Equine protozoal myeloencephalitis (EPM) is the most commonly diagnosed infectious neuro-degenerative condition in horses and neuroinflammation is present in all definitively diagnosed cases. Historically EPM is difficult to treat. Polyneuritis equi (cauda equina neuritis) is a rarely recognized noninfectious, chronic relapsing, peripheral neurodegenerative disorder in horses. We propose that p...

Bone Mineral Density in Children with Relapsing Nephrotic Syndrome

AbstractBackground: Given the high relapse rate of disease in children with steroid dependent nephrotic syndrome and the osteoporotic effect of long periods of steroid therapy, this survey was performed to find the bone mineral status of these patients. Methods: Bone mineral density and content (BMD and BMC) were measured using Dual energy X-ray absorptiometry in 37 nephrotic children, six girl...

Defining Relapses Attributed to Equine Protozoal Myeloencephalitis

Disease caused by Sarcocystis spp are associated with a variety of clinical signs including abortion, hemorrhages, hair loss, muscular disease, and neurological dysfunction. In horses, clinical disease is associated with Sarcocystis fayeri and S neurona. The genesis of and clinical progression of disease caused by these protozoans in horses is not well defined but acute, chronic, and relapsing ...

Dimethyl Fumarate Ameliorates Lewis Rat Experimental Autoimmune Neuritis and Mediates Axonal Protection

BACKGROUND Dimethyl fumarate is an immunomodulatory and neuroprotective drug, approved recently for the treatment of relapsing-remitting multiple sclerosis. In view of the limited therapeutic options for human acute and chronic polyneuritis, we used the animal model of experimental autoimmune neuritis in the Lewis rat to study the effects of dimethyl fumarate on autoimmune inflammation and neur...